- Americas Best Value Inn Tupelo
- Americas Best Value Inn Tupelo Barnes Crossing
- Baymont by Wyndham Tupelo
- Best Western Plus Tupelo Inn & Suites
- Candlewood Suites Tupelo North
- Comfort Inn
- Courtyard by Marriott Tupelo
- Days Inn by Wyndham Tupelo
- Econo Lodge
- Fairfield Inn & Suites by Marriott Tupelo
- Hampton Inn & Suites Tupelo/Barnes Crossing
- Hilton Garden Inn Tupelo
- Holiday Inn & Suites Tupelo North
- Holiday Inn Express & Suites Tupelo
- La Quinta Inn & Suites by Wyndham Tupelo
- Quality Inn
- Red Roof Inn Tupelo
- Spark by Hilton Tupelo
- Super 8 by Wyndham Tupelo Airport
- SureStay Hotel by Best Western Tupelo North